Pafolacianine 中文名
WebDec 12, 2024 · Pafolacianine Adult Medication This information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, … WebDec 1, 2024 · Cytalux (pafolacianine) injection is a sterile, non-pyrogenic, dark bluish green, clear aqueous solution for intravenous use. Each vial contains 3.2 mg (2 mg/mL) …
Pafolacianine 中文名
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WebAvoid coadministration with folic acid or folic acid-containing supplements for 48 hr before administering pafolacianine. Use of folate, folic acid, or folate-containing supplements … WebJan 6, 2024 · Pafolacianine sodium has a molecular formula of C 61 H 63 N 9 Na 4 O 17 S 4, a molecular mass of 1414.42 g/mol and has the following structure: CYTALUX …
WebMedKoo CAT#: 463874. CAS#: 1628423-76-6 (free acid) Description: Pafolacianine, also known as OTL0038 and OTL-38, is a folate receptor-directing imaging agent. OTL0038 accumulated at sites of inflammation in animal models. OTL-0038 displays high affinity and specificity for FRs and was shown (i) to accumulate in vivo in tumor cells expressing ... WebSep 7, 2024 · PURPOSE The adjunctive use of intraoperative molecular imaging (IMI) is gaining acceptance as a potential means to improve outcomes for surgical resection of targetable tumors. This confirmatory study examined the use of pafolacianine for real-time detection of folate receptor–positive ovarian cancer. METHODS This phase III, open …
WebPafolacianine, or OTL38, is a folate analogue conjugated with a fluorescent dye that absorbs light in the near-infrared (NIR) spectrum within a range of 760 nm to 785 nm, … WebMay 20, 2024 · Identification Summary. Pafolacianine is an optical imaging agent indicated in adult patients with ovarian cancer as an adjunct for intraoperative identification of …
Pafolacianine, sold under the brand name Cytalux, is an optical imaging agent used in fluorescence-guided surgery. Pafolacianine is a fluorescent medication that binds to folate receptor (FR)-expressing cells. The most common side effects of pafolacianine include infusion-related reactions, including … See more Pafolacianine is indicated as an adjunct for intraoperative identification of malignant lesions in people with ovarian cancer. It is also indicated to assist identifying lung cancer lesions in adults with known or suspected lung … See more The safety and effectiveness of pafolacianine was evaluated in a randomized, multi-center, open-label study of women diagnosed with ovarian cancer or with high clinical … See more • "Pafolacianine". Drug Information Portal. U.S. National Library of Medicine. • Clinical trial number NCT03180307 for "OTL38 for Intra-operative … See more refrigerator light bulb 7w led e26WebFeb 1, 2024 · Pafolacianine injection is used to help identify and remove ovarian cancer lesions during surgery. This medicine is to be given only by or under the direct supervision of a doctor with specialized training in near infrared imaging (NIR) systems. Before Using. Portions of this document last updated: Feb. 01, 2024. refrigerator life of watermelonWebFeb 1, 2024 · Pafolacianine injection is used to help identify and remove ovarian cancer lesions during surgery. This medicine is to be given only by or under the direct … refrigerator life precooked frozen lasagnaWebDec 1, 2024 · Pafolacianine is a fluorescent drug that targets folate receptor which may be overexpressed in ovarian cancer. It is used with a Near-Infrared (NIR) fluorescence … refrigerator light bulb intermittentWebDec 16, 2024 · The U.S. Food and Drug Administration has approved a new indication for Cytalux (pafolacianine) to assist surgeons in identifying lung cancer lesions in adult patients with known or suspected lung ... refrigerator light bulb part w10565137WebMEMORANDUM OF MEETING MINUTES Meeting Type: Type B Meeting Category: Pre-NDA Meeting Date and Time: Friday, November 13, 2024, 1:00 p.m. to 2:30 p.m. Application Number: IND 118215 Product Name: Pafolacianine sodium injection (OTL38 Injection) Indication: Sponsor’s Name: On Target Laboratories, Inc. Regulatory Pathway: 505(b)(1) … refrigerator light bulbs near meWebDec 16, 2024 · The U.S. Food and Drug Administration has approved a new indication for Cytalux (pafolacianine) to assist surgeons in identifying lung cancer lesions in adult … refrigerator light burned something