NettetAs discussed in the Summary section above, some studies have shown greater weight gain among people initiating INSTI-based regimens, particularly Black women. In a pooled analysis of eight randomized controlled trials in ART-naive individuals, the weight gain at 96 weeks with BIC- and DTG-based regimens was similar (approximately 3.5 kg). 7 Nettet17. mar. 2024 · At 18 months, PLWH on dolutegravir gained 6.0 kg, compared to 2.6 kg for NNRTIs (P < .05), and 0.5 kg for elvitegravir (P < .05). PLWH starting dolutegravir also gained more weight at 18 months compared to raltegravir (3.4 kg) and PIs (4.1 kg), though these differences were not statistically significant. Conclusions:
Evidence gaps on weight gain in people living with HIV: a scoping ...
Nettet2. aug. 2024 · Weight change with INSTI therapy appears to be heterogenous, however. While the average weight gain with INSTI use is moderate, some patients, such as our … NettetAlthough the highest mean weight gain of 3.2 kg was seen in those 90 patients switched from both TDF- to TAF-based and non INSTI- to INSTI-based ART (TAF/INSTI switch … proactive md greer
Mitochondrial DNA haplogroups and weight gain following... : AIDS
Nettet5. jun. 2024 · INSTIs have proven to be efficacious in virologic suppression in combination with other antiretrovirals (ARVs); however, recent data has demonstrated a potential linkbetween weight gain and... NettetINSTI , Weight Gain, Infezione da Hiv Potenziali conflitti di interesse: nessuno JHA 2024; 7(2): 25-28 DOI: 10.19198/JHA31532 Riassunto Grazie all’utilizzo di terapie antiretrovirali di combinazione (cART), l’infezione da HIV è ormai da considerarsi una con-dizione cronica, che necessita l’assunzione di farmaci per tutta la vita. Nettet8 timer siden · However, observational data shows that in PLWH, weight increases annually due to aging, but a more rapid increase may be observed in the first 6–12 months of therapy, particularly in people starting or switching to INSTIs. After this period, the WG trend may or may not return to parallel that observed in the general population [ 6 ]. proactive md corporate office